First syntheses of two quinoline alkaloids from the medicinal herb Ruta chalepensis via cyclization of an o-iodoaniline with an acetylenic sulfone.
نویسندگان
چکیده
The first syntheses of two quinoline alkaloids found in the medicinal herb Ruta chalepensis are reported via the conjugate addition of an o-iodoaniline to an acetylenic sulfone, followed by Pd-catalyzed carbonylation, intramolecular acylation of the corresponding sulfone-stabilized carbanion, and reductive desulfonylation.
منابع مشابه
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عنوان ژورنال:
- Chemical communications
دوره 16 شماره
صفحات -
تاریخ انتشار 2002